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June 23, 2025Results in EngineeringOpen Access

FSI analysis revealed significant variations in hemodynamic patterns near the stenosis, with increased velocity, high OSI, reduced WSS, and prolonged relative residence time at the sinus, underscoring the importance of FSI over rigid wall assumptions.

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Why the study?

Atherosclerosis is a serious cardiovascular disease due to its asymptomatic behavior at its initial stage, motivating investigation of hemodynamics and arterial wall-blood flow interactions in stenosed carotid arteries.

Population

Idealized stenosed carotid artery with approximately 20% stenosis

Comparison

Fluid-Structure Interaction approach vs rigid wall assumption

Design

Computational simulation study

Authors

NKNitesh KumarHGH GirishAGA. Ganesha

Discussion

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Overview

These simulation findings should not change practice for mild carotid disease; they leave open whether FSI metrics can refine plaque-vulnerability assessment.

Structured PICO

P
Population
Idealized computational model of a stenosed carotid artery with approximately 20% stenosis at the sinus region
I
Intervention
Fluid-Structure Interaction (FSI) analysis using a non-Newtonian Carreau-Yasuda model for blood flow and linear isotropic material for the arterial wall
C
Comparator
Rigid wall assumption
O
Outcome
Hemodynamic parameters including velocity, wall shear stress (WSS), oscillatory shear index (OSI), relative residence time (RRT), endothelial stimulation potential (ESP), vorticity, and helicitysurrogate

Fluid-structure interaction modeling of a stenosed carotid artery demonstrates significant hemodynamic alterations, such as elevated oscillatory shear index and reduced wall shear stress, which may accelerate atherosclerosis progression.

Limitations

  • Use of idealized geometry rather than patient-specific geometries
  • Use of linear isotropic material for arterial wall rather than hyperelastic properties

Cite This Study

Kumar et al. (2025) studied this question.

synapsesocial.com/papers/6a7fe3b8ec1eb8bfa53a968chttps://doi.org/10.1016/j.rineng.2025.105943
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fluid-structure interaction study of hemodynamics and its biomechanical influence on carotid artery atherosclerotic plaque deposits2023 · 34 citations
  2. 2Numerical simulation of blood flow in 3D CT-based healthy and atherosclerosis carotid artery bifurcation models to compare the hemodynamics and biomechanics using FSI method under realistic boundary conditions2025 · 2 citations
  3. 3Fluid structure interaction analysis to stratify the behavior of different atheromatous carotid plaques2022
  4. 4Hemodynamic Study of Blood Flow in the Carotid Artery With a Focus on Carotid Sinus Using Fluid-Structure Interaction2021 · 23 citations
  5. 5BIOMECHANICAL INVESTIGATION OF PULSATILE FLOW IN A THREE-DIMENSIONAL ATHEROSCLEROTIC CAROTID BIFURCATION MODEL2012 · 35 citations