Why the study?
Does off-pump CABG compared to on-pump CABG improve the antiplatelet effect of aspirin in patients undergoing coronary artery bypass grafting?
Population
29 patients undergoing coronary artery bypass grafting (CABG)
Comparison
Off-pump coronary artery bypass grafting… vs Conventional coronary artery bypass grafting…
Design
Cohort
Follow-up
5 days
Authors
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Aspirin responsiveness may differ by CABG technique; hypothesis-generating and requires randomized confirmation before practice change.
Does off-pump CABG compared to on-pump CABG improve the antiplatelet effect of aspirin in patients undergoing coronary artery bypass grafting?
Off-pump CABG preserves the antiplatelet effect of aspirin compared to on-pump CABG, likely due to reduced platelet turnover associated with cardiopulmonary bypass.
Zimmermann et al. (2005) studied this question.
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