Why the study?
Is subcortical noradrenergic neuronal excitation the source of sympathetic nervous system activation in essential hypertension?
Population
11 untreated hypertensive patients and 18 normotensive subjects
Comparison
Measurement of regional brain noradrenaline… vs Normotensive subjects
Design
Case-control
Authors
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Suggests subcortical noradrenergic drive in essential hypertension; hypothesis-generating and should not yet change practice.
Is subcortical noradrenergic neuronal excitation the source of sympathetic nervous system activation in essential hypertension?
Increased subcortical noradrenaline release is a possible cause of peripheral sympathetic activation in essential hypertension.
Ferrier et al. (1993) studied this question.
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