Population
Subfragment 2 (S-2) of myosin
Design
Preclinical
Authors
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Highlights myosin S-2 hinge as potential modulator of contractility; leaves open translation to human cardiac models.
The study identifies a specific endotherm assigned to the hinge region of myosin S-2, suggesting its coiled-coil structure is stabilized by a hydrophobic interface and charged interactions.
Swenson et al. (1980) studied this question.