Why the study?
Is the ACE gene I/D polymorphism associated with an increased risk of developing advanced diabetic nephropathy in type II diabetic patients?
Population
117 subjects from North India, comprising 59 type II diabetic patients with advanced diabetic nephropathy…
Comparison
287 bp insertion/deletion polymorphism of the… vs Normal healthy controls
Design
Case-control
Authors
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No association seen in North Indian type 2 diabetes; leaves open ACE I/D polymorphism relevance in diabetic nephropathy across populations.
Is the ACE gene I/D polymorphism associated with an increased risk of developing advanced diabetic nephropathy in type II diabetic patients?
The ACE gene I/D polymorphism does not appear to be a risk factor for advanced diabetic nephropathy in type II diabetic patients from North India.
Kumar et al. (2005) studied this question.
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