Population
Pig kidney cell line IB-RS-2, clone 60
Comparison
Adaptation to growth in suspension culture vs Monolayer cells (IB-RS-2, BHK) and suckling mice
Design
Preclinical
Follow-up
72 hours (for cell growth)
Authors
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May support scalable FMDV vaccine production in suspension culture; leaves open industrial feasibility pending validation.
The IB-RS-2 pig kidney cell line can be adapted to suspension culture while retaining high susceptibility to foot-and-mouth disease virus, indicating potential for industrial-scale vaccine production.
Chapman et al. (1971) studied this question.
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