Coronary Access and Percutaneous Coronary Intervention Up to 3 Years After Transcatheter Aortic Valve Implantation With a Balloon-Expandable Valve
Key result
Coronary access after TAVI with a balloon-expandable valve was required in 3.5% of patients within 3 years, achieving 100% procedural success and 97.9% clinical success for PCI.
Why the study?
As TAVI expands to younger, lower-risk patients who may require CAD treatment, post-TAVI coronary access and PCI are expected to increase, prompting evaluation of these procedures.
What is the incidence, success rate, and clinical impact of coronary access and PCI up to 3 years after TAVI with a balloon-expandable valve?
Population
1936 TAVI patients treated with the SAPIEN 3 transcatheter heart valve
Comparison
Patients with vs without coronary access up to 3 years after TAVI
Design
Retrospective European registry study
Follow-up
Up to 3 years
Authors
Discussion
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Member takes
Implication
Supports high post-TAVI PCI success when needed; leaves open generalizability to other valves and longer follow-up.
Study Design
Type
Cohort (n=1,936)
Multicenter
Yes
Structured PICO
What is the incidence, success rate, and clinical impact of coronary access and PCI up to 3 years after TAVI with a balloon-expandable valve?
P
Population
1,936 patients (mean age 81.6 years, 48% female) who underwent TAVI with a balloon-expandable valve in the SOURCE 3 European registry, followed for up to 3 years.
E
Exposure
Coronary access (CA) with or without percutaneous coronary intervention (PCI) up to 3 years after TAVI
C
Comparator
Patients who did not undergo coronary access after TAVI
O
Outcome
Clinical outcomes including cardiac mortality and procedural success of coronary access and PCI up to 3 years after TAVIhard clinical
Coronary access and PCI after TAVI with a balloon-expandable valve are infrequently needed within 3 years but are highly successful when required.
Cite This Study
Tarantini et al. (2020) conducted a cohort in Post-Transcatheter Aortic Valve Implantation (TAVI) (n=1,936). Coronary access (CA) after TAVI vs. No coronary access was evaluated on Coronary access success. Coronary access after TAVI with a balloon-expandable valve was required in 3.5% of patients within 3 years, achieving 100% procedural success and 97.9% clinical success for PCI.