Why the study?
Is HAV RNA detectable in the serum of patients with acute type A hepatitis during the early convalescent phase, and does it correlate with clinical markers?
Population
38 patients with type A acute hepatitis and 20 patients with non-A, non-B, non-C acute hepatitis (total n=58)
Comparison
Detection of hepatitis A virus RNA in serum by… vs Patients with non-A, non-B, non-C acute hepatitis
Design
Cohort
Authors
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Supports HAV RNA as diagnostic marker in acute type A hepatitis; hypothesis-generating, requires validation before clinical use.
Is HAV RNA detectable in the serum of patients with acute type A hepatitis during the early convalescent phase, and does it correlate with clinical markers?
HAV RNA is detectable in the serum of the majority of type A hepatitis cases during their early convalescent phase, and its presence correlates with transaminase levels.
Keiichi Fujiwara (1997) studied this question.