Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 8, 2003Journal of Medical Virology

HAV replication in acute hepatitis with typical and atypical clinical course

View Full Paper
Ask AI
Bookmark
Share

Population

66 consecutive patients with acute hepatitis A admitted to hospital

Design

Cohort

Authors

ESEvangelista SagnelliUniversity of Campania "Luigi Vanvitelli"NCNicola CoppolaUniversité Claude Bernard Lyon 1CMCecilia MarroccoUniversity of Campania "Luigi Vanvitelli"

Discussion

Loading...

Member takes

Implication

May support HAV RNA monitoring to flag prolonged hepatitis A; leaves open clinical utility pending prospective validation.

Structured PICO

P
Population
66 consecutive patients with acute hepatitis A admitted to hospital (57 typical course, 4 prolonged, 5 relapsing)
I
Intervention
Detection of plasma HAV RNA by RT-PCR
O
Outcome
Correlation between the length of viremia and the clinical course of hepatitis A virus (HAV) infectionsurrogate

Detection of plasma HAV RNA after 20 days of illness may predict a prolonged course of acute hepatitis A.

Cite This Study

Sagnelli et al. (2003) studied this question.

synapsesocial.com/papers/6a70511e5671bbf00bc2b007https://doi.org/10.1002/jmv.10455
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular epidemiology of an outbreak of hepatitis A in Italy1995 · 33 citations
  2. 2Frequent detection of hepatitis A viral RNA in serum during the early convalescent phase of acute hepatitis A1997 · 55 citations
  3. 3Frequent detection of hepatitis A viral RNA in serum during the early convalescent phase of acute hepatitis A1997 · 48 citations
  4. 4Chronic hepatitis A with persistent viral replication1996 · 52 citations
  5. 5Complete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses1987 · 385 citations