Key result
Fecal shedding of HAV RNA was detected in 50% (5 of 10) of adult patients after symptom onset, lasting up to 3 months, even after ALT levels normalized.
Why the study?
How long does fecal shedding of hepatitis A virus last in adult patients with sporadic hepatitis A?
Population
10 adult patients with sporadic hepatitis A
Design
Case_series
Follow-up
up to 3 months
Authors
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May extend transmission risk beyond symptom resolution; hypothesis-generating in small case series, larger studies needed.
Observational (n=10)
How long does fecal shedding of hepatitis A virus last in adult patients with sporadic hepatitis A?
Fecal shedding of HAV can last for months after resolution of symptoms, indicating patients could remain a source of transmission longer than previously thought.
Hiroshi Yotsuyanagi (1996) conducted an observational in Hepatitis A (n=10). Sporadic hepatitis A was evaluated on Fecal HAV RNA detection after onset of clinical symptoms. Fecal shedding of HAV RNA was detected in 50% (5 of 10) of adult patients after symptom onset, lasting up to 3 months, even after ALT levels normalized.
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