Population
Adipose tissue, preadipocytes, and adipocytes in rodents and humans (including transgenic mice models)
Design
Review
Authors
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May link adipose angiotensinogen to obesity progression; extends mechanistic insights but leaves clinical impact open.
Angiotensinogen and its products act locally in an autocrine/paracrine manner to promote adipocyte hypertrophy and fat mass enlargement.
Ailhaud et al. (2002) studied this question.
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