Population
Human fibroblasts
Comparison
Poliovirus infection vs Uninfected cells or cells treated with…
Design
Preclinical
Follow-up
5 hours postinfection
Authors
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Indicates virus-driven calcium elevation in infected cells; leaves open its contribution to pathogenesis or as a therapeutic target.
Poliovirus infection of human fibroblasts significantly increases intracellular calcium concentration via voltage-sensitive calcium channels, dependent on viral gene expression.
Irurzun et al. (1995) studied this question.
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