Population
Human cells (HeLa cells)
Comparison
Poliovirus infection vs Uninfected cells (implied)
Design
Preclinical
Authors
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May link poliovirus gene expression to host lipid remodeling; hypothesis-generating for metabolic antiviral targets.
Poliovirus infection in human cells activates phospholipase C acting on phosphatidylcholine, contributing to altered lipid metabolism during viral replication.
Irurzun et al. (1993) studied this question.
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