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May 1, 1980Clinical Physics and Physiological MeasurementOpen Access

The sequential measurement of ventricular volumes and cardiac output by radionuclides

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Why the study?

Can sequential measurements of absolute ventricular volumes and cardiac output be accurately determined from a single intravenous injection of 99 Tc m-labelled human serum albumin?

Population

12 resting patients and 6 normal subjects

Comparison

Sequential measurement of ventricular volumes… vs Baseline/resting measurements

Design

Other

Authors

WHW. J. HannanJohn Brown UniversityJVJan VojáčekCharles UniversityNDN J DewhurstEdinburgh Royal Infirmary

Discussion

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Overview

May enable repeatable radionuclide volume measurements in small cohorts; leaves open validation for routine clinical use.

Structured PICO

Can sequential measurements of absolute ventricular volumes and cardiac output be accurately determined from a single intravenous injection of 99 Tc m-labelled human serum albumin?

P
Population
12 resting patients and 6 normal subjects
I
Intervention
Sequential measurement of ventricular volumes and cardiac output using a single intravenous injection of 99 Tc m-labelled human serum albumin and gated blood pool imaging
C
Comparator
Baseline/resting measurements
O
Outcome
Absolute ventricular volumes, cardiac output, and stroke volumesurrogate

A single injection of 99 Tc m-labelled human serum albumin allows for reliable sequential measurements of ventricular volumes and cardiac output.

Cite This Study

Hannan et al. (1980) studied this question.

synapsesocial.com/papers/6a82aa6ffdcaa17bff6d08echttps://doi.org/10.1088/0143-0815/1/2/003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Effects of Isoprenaline, Atropine and Dobutamine on Ventricular Volume Curves Obtained by Radionuclide Ventriculography1980 · 18 citations
  2. 2Effects of beta-adrenergic blockade on the cardiac response to maximal and submaximal exercise in man.1965 · 478 citations
  3. 3Standard Techniques for the Measurement of Red‐Cell and Plasma Volume*1973 · 150 citations
  4. 4Left ventricular volumes by gated equilibrium radionuclide angiography: a new method.1979 · 210 citations
  5. 5Quantitative radiocardiographic evaluation of cardiac dynamics in man at rest and during exercise1979 · 20 citations