Population
Rat aortic strips
Comparison
Ryanodine and various stimulants vs Untreated preparations or different calcium media
Design
Preclinical
Authors
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Hypothesis-generating for distinct Ca2+ stores in vascular smooth muscle; leaves open any clinical translation.
Phenylephrine and caffeine mobilize Ca2+ from a ryanodine-sensitive store, whereas PGF2 alpha releases Ca2+ from a ryanodine-insensitive store in vascular smooth muscle.
Hisayama et al. (1990) studied this question.
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