September 1, 1995The Journal of Clinical Endocrinology & Metabolism

Altered relation between circulating levels of insulin-like growth factor-binding protein-1 and insulin in growth hormone-deficient patients and insulin-dependent diabetic patients compared to that in healthy subjects.

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Population

Patients with growth hormone levels below 0.2 microgram/L throughout 24 h, patients with insulin-dependent…

Design

Cross-sectional

Follow-up

24 hours

Authors

AHAgneta HildingKarolinska Institutet KBKerstin BrismarKarolinska University Hospital MDMarie DegerbladKarolinska University Hospital

Discussion

Member takes

Implication

Elevated IGFBP-1 in GH deficiency and IDDM should not yet change monitoring; leaves open its utility as an insulin-sensitivity marker.

Structured PICO

Population

Patients with growth hormone (GH) levels below 0.2 microgram/L throughout 24 h (n=23), patients with insulin-dependent diabetes mellitus (IDDM; n=9), and healthy subjects (n=12).

Comparator

Healthy subjects (n=12)

Outcome

Diurnal profiles of insulin-like growth factor-binding protein-1 (IGFBP-1) and insulinsurrogate

IGFBP-1 levels are elevated in relation to insulin levels in growth hormone-deficient patients and IDDM patients compared to healthy subjects.

Cite This Study

Hilding et al. (1995) studied this question.

synapsesocial.com/papers/6a82d8be9aaf5d32a4b28e7d https://doi.org/10.1210/jcem.80.9.7545695

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Altered relation between circulating levels of insulin-like growth factor-binding protein-1 and insulin in growth hormone-deficient patients and insulin-dependent diabetic patients compared to that in healthy subjects.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Altered relation between circulating levels of insulin-like growth factor-binding protein-1 and insulin in growth hormone-deficient patients and insulin-dependent diabetic patients compared to that in healthy subjects.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider