Key result
The addition of thoracic epidural analgesia to general anesthesia significantly shortened the time to extubation (301 vs 591 minutes) and intensive care unit stay compared to general anesthesia alone.
Why the study?
Does combined general and thoracic epidural anesthesia reduce postoperative ventilation time and intensive care unit stay in patients undergoing low-risk coronary artery bypass surgery?
RCT (n=80)
Open-label
Coin toss
No
Does combined general and thoracic epidural anesthesia reduce postoperative ventilation time and intensive care unit stay in patients undergoing low-risk coronary artery bypass surgery?
Absolute Event Rate: 301% vs 591%
p-value: p=<0.01
Adding thoracic epidural analgesia to general anesthesia for low-risk coronary artery bypass surgery significantly reduces postoperative ventilation time and ICU stay without compromising hemodynamic stability.
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Supports thoracic epidural use in low-risk CABG protocols; extends RCT evidence for multimodal anesthesia in cardiac surgery.
Obersztyn et al. (2018) conducted an RCT in Coronary artery disease requiring bypass surgery (n=80). Thoracic epidural analgesia vs. General anesthesia alone was evaluated on Time to extubation [min] (p=<0.01). The addition of thoracic epidural analgesia to general anesthesia significantly shortened the time to extubation (301 vs 591 minutes) and intensive care unit stay compared to general anesthesia alone.
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