Key result
Among US adults, hypertension was associated with a higher 10-year cumulative incidence of CVD mortality (8.2% vs 3.6%), though a majority of deaths in hypertensive adults were from non-CVD causes.
Why the study?
A substantial proportion of adults with hypertension die from causes other than cardiovascular disease, but the frequencies were unknown.
Population
23,622 participants with hypertension and 5,744 without hypertension aged ≥ 45 years
Comparison
Adults with hypertension vs adults without hypertension
Design
Prospective cohort study
Follow-up
Median 8.1 years
Authors
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Shifts emphasis to non-CVD mortality in hypertension; leaves open optimal strategies for comprehensive risk reduction.
Cohort (n=29,366)
Yes
Absolute Event Rate: 8.2% vs 3.6%
A majority of deaths among adults with hypertension are from non-cardiovascular causes, emphasizing the importance of comprehensive healthcare beyond cardiovascular risk management.
Foti et al. (2025) conducted a cohort in Hypertension (n=29,366). Hypertension vs. Without hypertension was evaluated on Adjudicated underlying cause of death (CVD mortality 10-year cumulative incidence). Among US adults, hypertension was associated with a higher 10-year cumulative incidence of CVD mortality (8.2% vs 3.6%), though a majority of deaths in hypertensive adults were from non-CVD causes.
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