Population
30- to 70-day-old Syrian cardiomyopathic (Bio 14.6) and normal hamsters
Comparison
Mechanical disruption and extraction of… vs Normal hamsters
Design
Preclinical
Authors
Loading...
Suggests membrane mechanical fragility in cardiomyopathic hamsters; hypothesis-generating for T-tubule defects, with no clinical implications.
The study suggests that T-tubule/junctional SR membranes are more easily extracted by mechanical disruption in cardiomyopathic hamsters, indicating an abnormality in the mechanical properties of the cell membrane.
Tawada-Iwata et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: