Population
7-month-old cardiomyopathic hamsters (BIO 53:58) and random-bred control hamsters
Comparison
Isolation and reconstitution of regulatory… vs Proteins from random-bred control hamsters
Design
Preclinical
Authors
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May contribute to contractile dysfunction in hamster cardiomyopathy models; leaves open relevance to human heart failure.
In cardiomyopathic hamsters, decreased calcium sensitivity and altered regulatory protein function may contribute to impaired cardiac function.
Ashwani Malhotra (1990) studied this question.
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