Key result
Coronary artery aneurysm after drug-eluting stent implantation was associated with a higher rate of major adverse cardiac events compared to controls (26.9% vs 2.2%, P<0.001).
Why the study?
Does the development of coronary artery aneurysm after drug-eluting stent implantation increase the risk of major adverse cardiac events compared to patients without aneurysm?
Cohort (n=347)
Does the development of coronary artery aneurysm after drug-eluting stent implantation increase the risk of major adverse cardiac events compared to patients without aneurysm?
Absolute Event Rate: 26.9% vs 2.2%
p-value: p=< 0.001
The development of coronary artery aneurysm after first-generation drug-eluting stent implantation is associated with a significantly increased long-term risk of major adverse cardiac events and stent thrombosis.
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Heightened post-DES surveillance may be warranted in affected patients; leaves open causality and need for prospective confirmation.
Joo et al. (2017) conducted a cohort in Coronary artery aneurysm after drug-eluting stent implantation (n=347). Coronary artery aneurysm vs. No coronary artery aneurysm was evaluated on Major adverse cardiac events (MACE), the composite of all-cause death, nonfatal myocardial infarction (MI), and target lesion revascularization (TLR) (p=< 0.001). Coronary artery aneurysm after drug-eluting stent implantation was associated with a higher rate of major adverse cardiac events compared to controls (26.9% vs 2.2%, P<0.001).
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