Why the study?
Do antianginal drugs (GTN, amlodipine, atenolol) affect platelet function in vivo in healthy volunteers?
Population
9 normal healthy volunteers
Design
Other
Authors
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May influence antianginal selection in patients with platelet-related risk; hypothesis-generating in healthy volunteers and leaves open effects in CAD.
Do antianginal drugs (GTN, amlodipine, atenolol) affect platelet function in vivo in healthy volunteers?
Different classes of antianginal medications have distinct effects on platelet behavior in vivo, with nitrates inhibiting and calcium antagonists or beta-blockers enhancing certain aspects of platelet activation.
Knight et al. (1997) studied this question.
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