Key result
Lower glucose effectiveness was strongly correlated with higher left ventricular mass index (r = -0.61, P <.0001) and a higher prevalence of left ventricular hypertrophy.
Population
Untreated, nondiabetic, and nonobese subjects recently diagnosed with stage I or high-normal blood pressure
Design
Cross-sectional
Authors
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Associated with higher LVMI in early hypertension; hypothesis-generating, does not yet inform practice or warrant intervention.
Cross-Sectional
Effect estimate: r = -0.61
Absolute Event Rate: 126.4% vs 94.8%
p-value: p=<.0001
In nonobese, glucose-tolerant subjects with early-stage hypertension, reduced glucose effectiveness is strongly associated with increased left ventricular mass, suggesting it may serve as an early marker of left ventricular hypertrophy.
Pablo Stiefel (2004) conducted a cross-sectional in Stage I hypertension or high-normal blood pressure. Glucose effectiveness (SG) vs. Higher glucose effectiveness was evaluated on Left ventricular mass (LVM) index (r = -0.61, p=<.0001). Lower glucose effectiveness was strongly correlated with higher left ventricular mass index (r = -0.61, P <.0001) and a higher prevalence of left ventricular hypertrophy.
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