April 23, 2011Diabetes CareOpen Access

Men with NGT ≥155 mg/dL had a higher LVMI than men with NGT <155 mg/dL (126.6 vs. 114.3 g/m²; P = 0.002) and a higher LVH prevalence (41.1 vs. 25.8%; P < 0.0001).

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Why the study?

Does a 1-hour postload plasma glucose ≥155 mg/dL associate with increased left ventricular mass index in never-treated hypertensive patients with normal glucose tolerance?

Population

767 never-treated hypertensive subjects (393 women and 374 men), mean age 49.6 ± 8.5 years.

Comparison

1-hour postload plasma glucose ≥155 mg/dL during… vs 1-hour postload plasma glucose <155 mg/dL in…

Design

Cross-sectional

Authors

ASAngela SciacquaHeart Failure & Transplant SMSofia MiceliMagna Graecia University GCG CarulloCTO Hospital

Discussion

Member takes

Overview

May flag higher LVH risk among normoglycemic hypertensives; leaves open causal links and need for prospective validation.

Structured PICO

Does a 1-hour postload plasma glucose ≥155 mg/dL associate with increased left ventricular mass index in never-treated hypertensive patients with normal glucose tolerance?

Population

767 never-treated hypertensive subjects (393 women and 374 men), mean age 49.6 ± 8.5 years.

Intervention

1-hour postload plasma glucose ≥155 mg/dL during an oral glucose tolerance test (OGTT) in subjects with normal glucose tolerance (NGT)

Comparator

1-hour postload plasma glucose <155 mg/dL in subjects with normal glucose tolerance (NGT)

Outcome

Left ventricular mass index (LVMI) and prevalence of left ventricular hypertrophy (LVH)surrogate

In never-treated hypertensive patients with normal glucose tolerance, a 1-hour postload plasma glucose ≥155 mg/dL is associated with worse insulin sensitivity and higher left ventricular mass index, comparable to patients with impaired glucose tolerance or diabetes.

Cite This Study

Sciacqua et al. (2011) studied this question.

synapsesocial.com/papers/6a70bac0febe604dd7098040 https://doi.org/10.2337/dc11-0155

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April 23, 2011Diabetes CareOpen Access

Men with NGT ≥155 mg/dL had a higher LVMI than men with NGT <155 mg/dL (126.6 vs. 114.3 g/m²; P = 0.002) and a higher LVH prevalence (41.1 vs. 25.8%; P < 0.0001).

View Full Paper

Ask AI

Bookmark

Why the study?

Does a 1-hour postload plasma glucose ≥155 mg/dL associate with increased left ventricular mass index in never-treated hypertensive patients with normal glucose tolerance?

Population

767 never-treated hypertensive subjects (393 women and 374 men), mean age 49.6 ± 8.5 years.

Comparison

1-hour postload plasma glucose ≥155 mg/dL during… vs 1-hour postload plasma glucose <155 mg/dL in…

Design

Cross-sectional

Authors

ASAngela SciacquaHeart Failure & Transplant SMSofia MiceliMagna Graecia University GCG CarulloCTO Hospital

Discussion

Member takes

Overview

May flag higher LVH risk among normoglycemic hypertensives; leaves open causal links and need for prospective validation.

Structured PICO

Does a 1-hour postload plasma glucose ≥155 mg/dL associate with increased left ventricular mass index in never-treated hypertensive patients with normal glucose tolerance?

Population

767 never-treated hypertensive subjects (393 women and 374 men), mean age 49.6 ± 8.5 years.

Intervention

1-hour postload plasma glucose ≥155 mg/dL during an oral glucose tolerance test (OGTT) in subjects with normal glucose tolerance (NGT)

Comparator

1-hour postload plasma glucose <155 mg/dL in subjects with normal glucose tolerance (NGT)

Outcome

Left ventricular mass index (LVMI) and prevalence of left ventricular hypertrophy (LVH)surrogate

Cite This Study

Sciacqua et al. (2011) studied this question.

synapsesocial.com/papers/6a70bac0febe604dd7098040 https://doi.org/10.2337/dc11-0155

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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