Population
Awake male Holtzman rats with stainless steel cannulas implanted bilaterally in the nucleus tractus solitarius
Comparison
Bilateral injections of muscimol or baclofen… vs Control responses to iv serotonin before the…
Design
Preclinical
Follow-up
60 min
Authors
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NTS GABA_A receptor activation attenuates Bezold-Jarisch reflex in rats; leaves open translation to human autonomic control.
Stimulation of GABA A receptors in the NTS of awake rats increases basal MAP and decreases the cardiac Bezold-Jarisch reflex responses to iv serotonin.
Callera et al. (2005) studied this question.
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