Why the study?
Does the duration of DAPT (abbreviated vs extended) affect coronary events and bleeding complications in patients undergoing PCI with current generation DES?
Does the duration of DAPT (abbreviated vs extended) affect coronary events and bleeding complications in patients undergoing PCI with current generation DES?
Abbreviated DAPT (<6 months) is a viable option for patients receiving current-generation DES, whereas extended DAPT (>1 year) should be reserved for those with high ischemic and low bleeding risks.
Shorter DAPT viable for many post-PCI patients with modern DES; extends prior meta-analyses by focusing on current-generation stents and risk-stratified use.
This meta-analysis suggests that abbreviated DAPT (<6 months) could be considered in patients undergoing PCI with current generation drug eluting stents (DES). Extended DAPT strategy (>1 year) may be appropriate in those patients in whom prevention of stent and non-stent-related coronary events are likely to offset the bleeding complications. Additional randomized trials are needed to evaluate the optimum duration of DAPT in patients with the latest generation DES and current antiplatelet drugs.
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Bang et al. (2016) studied this question.
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