June 1, 1985Annals of Internal Medicine
Adverse Cardiac Effects of Acute Alcohol Ingestion in Young Adults
Why the study?
Does acute oral alcohol ingestion reduce load-independent left ventricular contractility in healthy young adults?
Population
9 healthy, young adults
Comparison
Acute oral alcohol administration with… vs Baseline (before oral alcohol administration)
Authors
Discussion
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Member takes
Implication
May warrant caution with acute alcohol; leaves open relevance to patients with heart disease.
Structured PICO
Does acute oral alcohol ingestion reduce load-independent left ventricular contractility in healthy young adults?
P
Population
9 healthy, young adults
I
Intervention
Acute oral alcohol administration with methoxamine infusion
C
Comparator
Baseline (before oral alcohol administration)
O
Outcome
Load-independent end-systolic indices of left ventricular contractility (end-systolic pressure-dimension slope and rate-corrected velocity of left ventricular fiber shortening)surrogate
Acute alcohol ingestion has a significant myocardial depressant effect when assessed using load-independent measures of left ventricular contractility.
Cite This Study
Roberto M. Lang (1985) studied this question.