Why the study?
Does intravenous alcohol reduce left ventricular contractile performance in conscious dogs?
Population
10 healthy, adult mongrel dogs (weight 23-30 kg)
Comparison
Intravenous infusion of alcohol vs Baseline measurements before alcohol infusion in…
Design
Preclinical
Follow-up
20 minutes
Authors
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Mild alcohol depresses LV contractility in dogs; leaves open translation to human HF and should not yet change practice.
Does intravenous alcohol reduce left ventricular contractile performance in conscious dogs?
Mildly intoxicating levels of alcohol produce direct left ventricular contractile depression in conscious animals, suggesting that patients with impaired LV function should avoid even small amounts of alcohol.
Cheng et al. (1990) studied this question.
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