Why the study?
Does elevated Angiotensin II impair NO-dependent attenuation of sympathetic vasoconstriction in exercising muscle via reactive oxygen species in rats?
Population
Rats
Comparison
Chronic infusion of Angiotensin II or unilateral… vs Vehicle infusion, norepinephrine infusion, or…
Design
Preclinical
Authors
Loading...
Should not inform hypertension management; hypothesis-generating for ROS-mediated sympathetic dysregulation in exercising muscle.
Does elevated Angiotensin II impair NO-dependent attenuation of sympathetic vasoconstriction in exercising muscle via reactive oxygen species in rats?
Chronically elevated Angiotensin II increases muscle reactive oxygen species, disrupting the normal nitric oxide-dependent attenuation of sympathetic vasoconstriction during exercise.
Zhao et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: