March 1, 1979HypertensionOpen Access

Micromethod for the assay of renin of seven species.

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Population

Renin extracted and purified from human, dog, hog, rat, beef, rabbit and sheep kidneys

Design

Preclinical

Authors

EHE. HaasHokkaido University of Science LLL LewisLewis University PSP. ScipionePresidio Ospedaliero

Discussion

Member takes

Implication

Dog substrate may standardize cross-species renin assays in research; leaves open human diagnostic translation.

Structured PICO

Population

Renin extracted and purified from human, dog, hog, rat, beef, rabbit and sheep kidneys

Intervention

In vitro incubation with renin substrate prepared from the serum of nephrectomized dogs or hog plasma

Outcome

Rate of angiotensin formationsurrogate

Renin substrate from nephrectomized dogs provides a uniform assay for renin across seven species, allowing standardization against WHO reference preparations.

Cite This Study

Haas et al. (1979) studied this question.

synapsesocial.com/papers/6a83c545f4298de60b3c2bea https://doi.org/10.1161/01.hyp.1.2.112

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Ask AI

Bookmark

Micromethod for the assay of renin of seven species.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Micromethod for the assay of renin of seven species.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider