July 1, 1972Circulation ResearchOpen Access

Studies on Renin

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Population

Normal conscious dogs and rats (for bioassay)

Comparison

Simplified method for the indirect assay of… vs Previous direct bioassay of renin

Design

Preclinical

Authors

EHErwin HaasCedars-Sinai Medical Center HGHarry GoldblattFood and Agriculture Organization of the United Nations LLL LewisLewis University

Discussion

Member takes

Implication

Improved canine renin assay sensitivity aids experimental standardization; extends preclinical tools but leaves clinical translation open.

Structured PICO

Population

Normal conscious dogs and rats (for bioassay)

Intervention

Simplified method for the indirect assay of canine renin and prolonged infusion of renin

Comparator

Previous direct bioassay of renin

Outcome

Sensitivity and accuracy of the renin assaysurrogate

A highly sensitive and accurate indirect bioassay for canine renin was developed, enabling precise measurement of endogenous renin and standardization across laboratories.

Cite This Study

Haas et al. (1972) studied this question.

synapsesocial.com/papers/6a89a8ce273d243e4992e59a https://doi.org/10.1161/01.res.31.1.65

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Implication

Improved canine renin assay sensitivity aids experimental standardization; extends preclinical tools but leaves clinical translation open.

Studies on Renin

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Studies on Renin

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider