Why the study?
Does long-term administration of tibolone affect carotid artery intima-media thickness or prevalence of plaques in postmenopausal women?
Population
61 postmenopausal women (31 on tibolone and 30 voluntary controls)
Comparison
Long-term administration of tibolone vs Voluntary controls
Design
Cohort, open-label
Follow-up
long-term
Authors
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Long-term tibolone warrants no carotid monitoring adjustment; leaves open its net cardiovascular effects without randomized trials.
Does long-term administration of tibolone affect carotid artery intima-media thickness or prevalence of plaques in postmenopausal women?
Long-term use of tibolone in postmenopausal women does not appear to significantly affect carotid intima-media thickness or plaque prevalence.
Morris et al. (1999) studied this question.
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