Population
Drosophila ether-à-go-go K(+) channel (eag) (studied via cut-open oocyte voltage clamp)
Comparison
Extracellular Mg and prepulse hyperpolarization vs Without prepulse hyperpolarization or…
Design
Preclinical
Authors
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Mg2+ effects on eag gating merit investigation in mammalian cardiac models; leaves open clinical relevance for arrhythmia.
Extracellular Mg2+ and prepulse hyperpolarization modulate the voltage-dependent gating and pore opening of Drosophila eag potassium channels, involving the S3-S4 loop.
Tang et al. (2000) studied this question.
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