Why the study?
Does intra-arterial prostaglandin E1 prevent amputation in patients with inoperable occlusion of the arteries of the lower limbs?
Population
100 patients suffering from inoperable occlusion of the arteries of the lower limbs and facing amputation
Design
Case_series
Follow-up
average period of 34 days (treatment duration)
Authors
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May support selective limb salvage with intra-arterial PGE1; leaves open efficacy in inoperable lower-limb ischemia pending controlled trials.
Does intra-arterial prostaglandin E1 prevent amputation in patients with inoperable occlusion of the arteries of the lower limbs?
Intra-arterial prostaglandin E1 perfusion may help salvage limbs in patients with inoperable lower extremity arterial occlusions, with better outcomes observed in thromboangiitis obliterans compared to insulin-requiring diabetes.
Gruß et al. (1982) studied this question.
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