Population
Human mesangial cells
Comparison
Phosphatase inhibitors and dibutyryl cGMP vs Control conditions
Design
Preclinical
Authors
Loading...
PP2A may modulate BKCa in mesangial cells; leaves open its role in glomerular disease models.
Protein phosphatase 2A (PP2A) inactivates large calcium-activated potassium channels (BKCa) in human mesangial cells, counteracting their activation by cGMP-activated protein kinase.
Sansom et al. (1997) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: