Why the study?
Does switching to amisulpride compared to olanzapine improve heart rate variability in schizophrenia patients?
Population
33 schizophrenia patients switched from typical antipsychotics to atypical antipsychotic agents due to…
Comparison
Switch to amisulpride vs Switch to olanzapine
Design
Cohort
Follow-up
3 months
Authors
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Amisulpride was associated with greater HRV gains than olanzapine; hypothesis-generating for CV safety, prospective trials needed.
Does switching to amisulpride compared to olanzapine improve heart rate variability in schizophrenia patients?
Switching from typical antipsychotics to amisulpride, but not olanzapine, significantly increases heart rate variability, suggesting a more favorable cardiovascular safety profile.
Wang et al. (2008) studied this question.
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