Why the study?
Does the lung inflation reflex attenuate vasoconstrictor responses in renal cortex and splanchnic beds during severe arterial hypoxia in dogs?
Population
Chloralose-anesthetized dogs
Comparison
Severe arterial hypoxia induced by inspiration… vs Comparison between different ventilation…
Design
Preclinical
Authors
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Lung inflation reflex does not protect renal/splanchnic beds from hypoxia-induced vasoconstriction in dogs; leaves open translation to human physiology.
Does the lung inflation reflex attenuate vasoconstrictor responses in renal cortex and splanchnic beds during severe arterial hypoxia in dogs?
The lung inflation reflex does not attenuate hypoxia-induced vasoconstriction in renal and splanchnic beds in a canine model.
Crystal et al. (1986) studied this question.
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