Why the study?
Do patients with irritable bowel syndrome have altered autonomic nervous system function as measured by spectral analysis of heart rate variability compared to matched controls?
Population
18 patients with irritable bowel syndrome (IBS) and 36 sex- and age-matched controls (n=54)
Comparison
Irritable bowel syndrome (exposure) vs Sex- and age-matched controls
Design
Case-control
Authors
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May indicate sympathetic predominance in IBS; hypothesis-generating and should not yet change practice.
Do patients with irritable bowel syndrome have altered autonomic nervous system function as measured by spectral analysis of heart rate variability compared to matched controls?
Patients with irritable bowel syndrome exhibit significantly increased sympathetic autonomic activity compared to healthy controls, as measured by heart rate variability.
Pontus Karling (1998) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: