Why the study?
Does irritable bowel syndrome alter cardiac sympatho-vagal balance during waking and sleep compared to healthy controls?
Population
30 subjects: 15 patients with irritable bowel syndrome and 15 healthy controls.
Comparison
Irritable bowel syndrome (observational exposure) vs Healthy controls
Design
Case-control
Follow-up
1 hour of pre-sleep quiet waking and 7 hours of sleep
Authors
Loading...
May indicate autonomic imbalance in IBS; hypothesis-generating and should not yet alter practice or risk stratification.
Does irritable bowel syndrome alter cardiac sympatho-vagal balance during waking and sleep compared to healthy controls?
Patients with irritable bowel syndrome exhibit greater sympathetic activity during waking and sympathetic dominance during REM sleep, suggesting autonomic abnormalities.
Orr et al. (2000) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: