Key result
IBS-only patients demonstrated greater sympathetic dominance during REM sleep compared to IBS+D patients and controls, driven by significant vagal withdrawal and an elevated LF/HF ratio.
Why the study?
Does heart rate variability during REM sleep differentiate irritable bowel syndrome symptom subgroups?
Population
33 female irritable bowel syndrome patients stratified into 16 subjects with only lower bowel symptoms and…
Comparison
Heart rate variability analysis via… vs Healthy controls and IBS patients with both…
Design
Cross-sectional
Authors
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HRV during REM may differentiate IBS subgroups; leaves open utility for autonomic stratification.
Observational (n=54)
Does heart rate variability during REM sleep differentiate irritable bowel syndrome symptom subgroups?
Heart rate variability analysis during REM sleep identifies distinct autonomic profiles in IBS subgroups, suggesting its potential as a biological marker for patient stratification.
Thompson et al. (2002) conducted an observational in Irritable bowel syndrome (n=54). IBS symptom subgroups (IBS-only vs IBS+D) vs. Healthy controls was evaluated on High-frequency band power and low-frequency/high-frequency ratio during REM sleep. IBS-only patients demonstrated greater sympathetic dominance during REM sleep compared to IBS+D patients and controls, driven by significant vagal withdrawal and an elevated LF/HF ratio.
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