Why the study?
Can a minimal intraarterial plasma concentration (MIC BAR) of fentanyl be identified to prevent hypertensive responses to noxious stimuli in patients undergoing aortocoronary bypass surgery?
Population
n=43 patients with good left ventricular function undergoing aortocoronary bypass surgery, premedicated with…
Design
Cohort
Follow-up
intraoperative
Authors
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Interpatient variability precludes a reliable MIC BAR; leaves open individualized titration strategies in cardiac anesthesia.
Can a minimal intraarterial plasma concentration (MIC BAR) of fentanyl be identified to prevent hypertensive responses to noxious stimuli in patients undergoing aortocoronary bypass surgery?
A minimal intraarterial plasma concentration of fentanyl to prevent hypertensive responses during cardiac surgery could not be identified due to high inter-patient variability.
Wynands et al. (1984) studied this question.
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