January 1, 1996Journal of Cardiovascular Pharmacology

Neurons and Receptors in the Rostroventrolateral Medulla Mediating the Antihypertensive Actions of Drugs Acting at Imidazoline Receptors

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Design

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Authors

DRDonald J. ReisCornell University

Discussion

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Implication

May support preferring moxonidine or rilmenidine to limit somnolence; leaves open head-to-head RCTs versus nonselective agents.

Structured PICO

Intervention

Antihypertensive agents acting at imidazoline receptors (clonidine, moxonidine, rilmenidine)

Outcome

Blood pressure reduction and somnolence

Selective imidazoline-receptor agonists like moxonidine and rilmenidine may offer antihypertensive efficacy with fewer side effects like somnolence compared to non-selective agents.

Cite This Study

Donald J. Reis (1996) studied this question.

synapsesocial.com/papers/6a854491c12175303ef23ce9 https://doi.org/10.1097/00005344-199627003-00003

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Neurons and Receptors in the Rostroventrolateral Medulla Mediating the Antihypertensive Actions of Drugs Acting at Imidazoline Receptors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Neurons and Receptors in the Rostroventrolateral Medulla Mediating the Antihypertensive Actions of Drugs Acting at Imidazoline Receptors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider