Population
BHK-21 cells transfected with bicistronic plasmids containing Equine rhinitis A virus 5' nontranslated region
Comparison
Mutational analysis of AUG codons and IRES… vs Foot-and-mouth disease virus translation…
Design
Preclinical
Authors
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Remains preclinical without human data; leaves open IRES-targeted strategies for aphthoviruses pending further validation.
This study reveals important differences in IRES function and translation initiation between aphthoviruses ERAV and FMDV.
Hinton et al. (2000) studied this question.
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