Why the study?
Do different forms of a novel autologous aortic valve (biovalve) affect regurgitation rate and durability in an in vitro pulsatile circulation circuit?
Do different forms of a novel autologous aortic valve (biovalve) affect regurgitation rate and durability in an in vitro pulsatile circulation circuit?
A novel autologous biovalve with extended leaflets demonstrated low regurgitation and high durability in an in vitro mock circulation model, suggesting potential for future use in aortic valve replacement.
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Extended biovalves merit in vivo testing; leaves open clinical translation for aortic valve replacement.
Sumikura et al. (2013) studied this question.
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