Why the study?
Does central or peripheral infusion of hypertonic NaCl improve hemodynamic responses to hemorrhage in conscious and anesthetized sheep?
Does central or peripheral infusion of hypertonic NaCl improve hemodynamic responses to hemorrhage in conscious and anesthetized sheep?
Intact autonomic cardiovascular control is crucial for the hemodynamic benefits of central hypertonic saline during hemorrhage, suggesting intravenous hypertonic saline exerts part of its action centrally.
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Intact autonomic control is required for central hypertonic NaCl benefits in conscious hemorrhage; leaves open translation to clinical resuscitation.
Frithiof et al. (2006) studied this question.
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