Key result
Heart-type fatty acid-binding protein demonstrated higher sensitivity (75.76%) than troponin T (58.59%) and CK-MB (68.69%) for identifying acute coronary syndrome in the first 6 hours.
Why the study?
Does h-FABP point-of-care testing improve the early diagnosis of acute myocardial infarction compared to troponin T and CK-MB in patients presenting with chest pain?
Population
791 patients presenting with chest pain with duration since onset ranging from 20 minutes to 12 hours
Comparison
Heart-type fatty acid-binding protein… vs Troponin T and Creatine kinase
Design
Cross-sectional
Authors
Loading...
May support earlier ACS detection in chest pain; hypothesis-generating and requires prospective validation before practice change.
Observational (n=791)
Does h-FABP point-of-care testing improve the early diagnosis of acute myocardial infarction compared to troponin T and CK-MB in patients presenting with chest pain?
Absolute Event Rate: 75.76% vs 58.59%
Point-of-care h-FABP testing offers higher sensitivity than troponin T and CK-MB for detecting myocardial infarction within the first 6 hours of chest pain onset.
Naroo et al. (2009) conducted an observational in Acute coronary syndrome (n=791). Heart-type fatty acid-binding protein (h-FABP) vs. Troponin T and CK-MB was evaluated on Sensitivity for identifying acute coronary syndrome in the first 6 hours. Heart-type fatty acid-binding protein demonstrated higher sensitivity (75.76%) than troponin T (58.59%) and CK-MB (68.69%) for identifying acute coronary syndrome in the first 6 hours.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: