August 1, 1978European Journal of Biochemistry

Interaction of Human Blood Platelets with the 2′,3′‐Dialdehyde and 2′,3′‐Dialcohol Derivatives of Adenosine 5′‐Diphosphate and Adenosine 5′‐Triphosphate

View Full Paper

Ask AI

Bookmark

Population

Human blood platelets

Design

Preclinical

Authors

PPP.H. PearceThe University of Western Australia JWJudith WrightUniversity of London CEChristopher M. EganTrinity College Dublin

Discussion

Member takes

Implication

Hypothesis-generating for ADP receptor modulation in platelets; animal data leave open human applicability.

Structured PICO

Population

Human blood platelets

Intervention

2',3'-dialdehyde and 2',3'-dialcohol derivatives of ADP and ATP (oADP, oATP, orADP, orATP)

Outcome

Platelet shape change and aggregationsurrogate

The 2',3'-dialdehyde and dialcohol derivatives of ADP and ATP modulate human platelet aggregation and shape change, with orADP acting as a classical ADP receptor antagonist.

Cite This Study

Pearce et al. (1978) studied this question.

synapsesocial.com/papers/6a85c066b451cea71dae79f0 https://doi.org/10.1111/j.1432-1033.1978.tb12480.x

View Full Paper

Ask AI

Bookmark

Interaction of Human Blood Platelets with the 2′,3′‐Dialdehyde and 2′,3′‐Dialcohol Derivatives of Adenosine 5′‐Diphosphate and Adenosine 5′‐Triphosphate

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Interaction of Human Blood Platelets with the 2′,3′‐Dialdehyde and 2′,3′‐Dialcohol Derivatives of Adenosine 5′‐Diphosphate and Adenosine 5′‐Triphosphate

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider