Why the study?
Does subintimal percutaneous transluminal angioplasty induce platelet activation and thrombin generation in patients with intermittent claudication?
Population
10 patients with intermittent claudication undergoing successful subintimal percutaneous transluminal…
Comparison
Subintimal percutaneous transluminal angioplasty vs Preprocedural and pre-entry blood samples
Design
Cohort
Follow-up
24 hours
Authors
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Transient prothrombotic effects after subintimal PTA in claudication merit safety evaluation; leaves open optimal periprocedural antithrombotic strategies.
Does subintimal percutaneous transluminal angioplasty induce platelet activation and thrombin generation in patients with intermittent claudication?
Subintimal percutaneous transluminal angioplasty induces extremely rapid and substantial uniform platelet activation and thrombin generation that normalizes within 24 hours.
Jenssen et al. (2011) studied this question.
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