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February 8, 2005HypertensionOpen Access

Aortic Diameter, Aortic Stiffness, and Wave Reflection Increase With Age and Isolated Systolic Hypertension

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Population

Aging individuals and patients with isolated systolic hypertension

Design

Review

Authors

MOMichael F. O’RourkeWNWilmer W. Nichols

Discussion

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Overview

Reinforces wave reflection as therapy target in systolic hypertension; leaves open prospective outcome trials before practice change.

Structured PICO

P
Population
Aging individuals and patients with isolated systolic hypertension
O
Outcome
Changes in aortic diameter, aortic stiffness, and wave reflectionsurrogate

This review reinforces the conventional view that early wave reflection is the primary vascular consequence of aging and a key therapeutic target in isolated systolic hypertension.

Cite This Study

O’Rourke et al. (2005) studied this question.

synapsesocial.com/papers/6a8663623e3615047d999fechttps://doi.org/10.1161/01.hyp.0000153793.84859.b8
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