Population
Rat tibialis anterior (TA) and soleus muscles
Comparison
Chronic low-frequency stimulation (12-h and 4-day) vs Control (unstimulated) TA muscles
Design
Preclinical
Follow-up
Up to 4 days
Authors
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MLP upregulation during muscle stimulation may mark cytoskeletal remodeling; leaves open its role in human fiber-type plasticity.
Muscle LIM protein is upregulated during the fast-to-slow transition in skeletal muscle induced by chronic low-frequency stimulation, suggesting a role in cytoskeletal or myofibrillar rearrangement.
Schneider et al. (1999) studied this question.
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